Our research

Amongst all current imaging modalities, optical microscopy is the only method capable of probing live tissue with cellular and subcellular resolution and is the only one with a broad range of molecular contrast mechanisms. This versatility comes from the fact that the photon energy is comparable to that of molecular orbitals and consequently, contrasts based on density, absorption, fluorescence, and coherent nonlinear interactions are possible. Imaging strategies based on novel contrast mechanisms can be developed and integrated into current technology to enhance a biologist’s toolbox, or can be developed into new imaging devices to enable innovative applications in life sciences.

Spinnning endoscope to image with cellular resolution cells in deep areas of the brain

Our group stands at the interface between optical technologies and biology, and we pursue a research program that has the following long-term objectives:

  1. To develop and adapt novel optical contrast mechanisms to biological imaging,
  2. To build new devices optimized for biological imaging applications,
  3. To combine these optical techniques and devices for innovative biology applications.

We fulfill these goals through collaborative projects with our biologist colleagues that build on the expertise of our multidisciplinary team.

Daniel Côté's laboratory at Neurophotonics Center, Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec